Squamous cell carcinomas (SCC) are all cancers that affect the squamous epithelial cell layer. These cancers may form in many different sites of the body, including internal cavities that are covered by the squamous epithelium. SCCs include certain types of esophageal cancers, one-third of all lung cancers, head and neck cancer and 75% of all uterine cervix cancers. Its association with tobacco exposure and alcohol abuse makes the head and neck region susceptible to SCC, accounting for over 90% of all head and neck cancers. When these carcinomas are treated promptly, and before they are able to spread, patients will have a better chance of recovery. Therefore diagnostics that for early detection become increasingly important.