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updated 14.10.2019

Hepa-AB Literature

48. Turato C, Fornari F, Pollutri D, Fassan M, Quarta S, Villano G, Ruvoletto M, Bolondi L, Gramantieri L, Pontisso P. MiR-122 Targets SerpinB3 and Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma.. J Clin Med. 8(2). 2019. doi: 10.3390/jcm8020171
47. Liu J, Gao Y, Yang B, Jia X, Zhai D, Li S, Zhang Q, Jing L, Wang Y, Du Z, Wang Y. Overexpression of Squamous Cell Carcinoma Antigen 1 Is Associated with the Onset and Progression of Human Hepatocellular Carcinoma. Arch. Med. Res. 46(2):133-141. 2015. doi: 10.1016/j.arcmed.2015.03.003
46. Martini A, Fattovich G, Guido M, Bugianesi E, Biasiolo A, Ieluzzi D, Gallotta A, Fassina G, Merkel C, Gatta A, Negro F, Pontisso P. HCV genotype 3 and squamous cell carcinoma antigen (SCCA)-IgM are independently associated with histological features of NASH in HCV-infected patients. J Viral Hepat. 22(10):800-808. 2015. doi: 10.1111/jvh.12394
45. Fadini GP, Albiero M, Millioni R, Poncina N, Rigato M, Scotton R, Boscari F, Brocco E, Arrigoni G, Villano G, Turato C, Biasiolo A, Pontisso P, Avogaro A. The molecular signature of impaired diabetic wound healing identifies serpinB3 as a healing biomarker. Diabetologia. 57(9):1947-56. 2014. doi: 10.1007/s00125-014-3300-2
44. Pontisso P. Role of SERPINB3 in hepatocellular carcinoma. Ann Hepatol. 13(6):722-727. 2014.
43. Calabrese F, Lunardi F, Balestro E, Marulli G, Perissinotto E, Loy M, Nannini N, Valente M, Saetta M, Agostini C, Rea F. Serpin B4 isoform overexpression is associated with aberrant epithelial proliferation and lung cancer in idiopathic pulmonary fibrosis. Pathology. 44(3):192-198. 2012. doi: 10.1097/PAT.0b013e3283511b61
42. Turato C, Buendia MA, Fabre M, Redon MJ, Branchereau S, Quarta S, Ruvoletto M, Perilongo G, Grotzer MA, Gatta A, Pontisso P. Over-expression of SERPINB3 in hepatoblastoma: a possible insight into the genesis of this tumour?. Eur J Cancer. 48(8):1219-26. 2012. doi: 10.1016/j.ejca.2011.06.004
41. Schmilovitz-Weiss H, Tobar A, Halpern M, Levy I, Shabtai E, Ben-Ari Z. Tissue expression of squamous cellular carcinoma antigen and Ki67 in hepatocellular carcinoma-correlation with prognosis: A historical prospective study. Diagn Pathol. 6:121. 2011. doi: 10.1186/1746-1596-6-121
40. Turato C, Buendia MA, Fabre M, Redon MJ, Branchereau S, Quarta S, Ruvoletto MG, Perilongo G, Grotzer MA, Gatta A, Pontisso P. Over-expression of SERPINB3 in hepatoblastoma: a possible insight into the genesis of this tumor?. Dig Liver Dis. 43(S2):S66. 2011. doi: 10.1016/S1590-8658(11)60005-4
39. Quarta S, Vidalino L, Turato C, Ruvoletto MG, Calabrese F, Valente M, Cannito S, Fassina G, Parola M, Gatta A, Pontisso P. SERPINB3 induces epithelial-mesenchymal transition. J Pathol. 221(3):343-56. 2010. doi: 10.1002/path.2708
38. Turato C, Calabrese F, Biasiolo A, Quarta S, Ruvoletto MG, Tono N, Paccagnella D, Fassina G, Merkel C, Harrison TJ, Gatta A, Pontisso P. SERPINB3 modulates TGF-beta expression in chronic liver disease. Lab Invest. 90(7):1016-23. 2010. doi: 10.1038/labinvest.2010.55
37. Villano G, Quarta S, Ruvoletto MG, Turato C, Vidalino L, Biasiolo A, Tono N, Lunardi F, Calabrese F, Dall'olmo L, Dedja A, Fassina G, Gatta A, Pontisso P. Role of squamous cell carcinoma antigen-1 on liver cells after partial hepatectomy in transgenic mice. Int J Mol Med. 25(1):137-43. 2010. doi: 10.3892/ijmm_00000323
36. Cannito S, Turato C, Quarta S, Colombatto S, Biasiolo A, Pontisso P, Parola M. Hypoxia up-regulates SERPINB3 in HEPG2 cells: a redox sensitive event related to epithelial to mesenchymal transition and invasiveness. Dig Liver Dis. 41(3):A31-A32. 2009. doi: 10.1016/j.dld.2008.12.066
35. Cannito S, Turato C, Quarta S, Paternostro C, Colombatto S, Biasiolo A, Pontisso P, Parola M. Serpin B3 up-regulation by hypoxia in HepG2 cells: A redox sensitive, Ras/ERK and PI3-K mediated event related to invasiveness and epithelial to mesenchymal transition. Dig Liver Dis. 41(3):A19. 2009. doi: 10.1016/j.dld.2009.02.046
34. Hayashi M, Tomita S, Fujimori T, Nagata H, Kubota K, Shoda A, Tada K, Kosaka N, Fukasawa I, Inaba N. Retrorectal epidermoid cyst with unusually elevated serum SCC level, initially diagnosed as an ovarian tumor. Rare Tumors. 1(2):e21. 2009. doi: 10.4081/rt.2009.e21
33. Lunardi F, Pontisso P, Rea F, Villano G, Gnoato M, Agostini C, Calabrese F. Overexpression of Serpin B3 promotes epithelial instability in bleomicyn lung injury. Eur Respir J. 54:E3092. 2009.
32. Lunardi F, Pontisso P, Rea F, Villano G, Gnoato M, Agostini C, Valente M, Calabrese F. Serpin B3 transgenic mice are more susceptible to lung fibrosis and epithelial proliferation. Virchows Arch. 455(S1):S84. 2009. doi: 10.1007/s00428-009-0805-z
31. Quarta S, Vidalino L, Turato C, Ruvoletto M, Calabrese F, Fassina G, Gatta A, Pontisso P. SERPINB3 induces epithelial mesenchymal transition. Dig Liver Dis. 41(5):A1-A2. 2009. doi: 10.1016/j.dld.2009.02.012
30. Quarta S, Villano G, Turato C, Biasiolo A, Vidalino L, Ruvoletto M, Tono N, Calabrese F, Nicolosi L, Bernardi P, Gatta A, Pontisso P. Hepatic progenitor cells overexpress SERPINB3 in a mouse model of fulminant hepatitis. J Hepatol. 50:S312. 2009. doi: 10.1016/S0168-8278(09)60858-8
29. Trerotoli P, Fransvea E, Angelotti U, Antonaci G, Lupo L, Mazzocca A, Mangia A, Antonaci S, Giannelli G. Tissue expression of Squamous Cellular Carcinoma Antigen (SCCA) is inversely correlated to tumor size in HCC. Mol Cancer. 8:29. 2009. doi: 10.1186/1476-4598-8-29
28. Turato C, Calabrese F, Biasiolo A, Quarta S, Ruvoletto M, Tono N, Franzosi L, Paccagnella D, Fassina G, Gatta A, Pontisso P. SERPINB3 and TGF-beta1 in chronic liver disease. Dig Liver Dis. 41(3):A13-A14. 2009. doi: 10.1016/j.dld.2008.12.030
27. Turato C, Calabrese F, Biasiolo A, Quarta S, Ruvoletto M, Tono N, Franzosi L, Paccagnella L, Fassina G, Gatta A. SERPINB3 and TGF-beta1 correlation in chronic liver disease. J Hepatol. 50:S117. 2009. doi: 10.1016/S0168-8278(09)60302-0
26. Turato C, Ruvoletto MG, Biasiolo A, Quarta S, Tono N, Bernardinello E, Beneduce L, Fassina G, Cavalletto L, Chemello L, Merkel C, Gatta A, Pontisso P. Squamous cell carcinoma antigen-1 (SERPINB3) polymorphism in chronic liver disease. Dig Liver Dis. 41(3):212-216. 2009. doi: 10.1016/j.dld.2008.06.001
25. Vidalino L, Doria A, Quarta S, Zen M, Gatta A, Pontisso P. SERPINB3, apoptosis and autoimmunity. Autoimmun Rev. 9(2):108-12. 2009. doi: 10.1016/j.autrev.2009.03.011
24. Villano G, Turato C, Campagna F, Schiff S, Calabrese F, Gatta A, Amodio P, Pontisso P. Role of microglial activation via SERPINB3 in experimental acute hepatic encephalopathy. J Hepatol. 50:S71. 2009. doi: 10.1016/S0168-8278(09)60170-7
23. Beale G, Chattopadhyay D, Gray J, Stewart S, Hudson M, Day C, Trerotoli P, Giannelli G, Manas D, Reeves H. AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease. BMC Cancer. 8:200. 2008. doi: 10.1186/1471-2407-8-200
22. Calabrese F, Giacometti C, Lunardi F, Valente M. Morphological and molecular markers in idiopathic pulmonary fibrosis. Expert Rev Respir Med. 2(4):505-520. 2008. doi: 10.1586/17476348.2.4.505
21. Calabrese F, Lunardi F, Giacometti C, Marulli G, Gnoato M, Pontisso P, Saetta M, Valente M, Rea F, Perissinotto E, Agostini C. Overexpression of squamous cell carcinoma antigen in idiopathic pulmonary fibrosis: clinicopathological correlations. Thorax. 63(9):795-802. 2008. doi: 10.1136/thx.2007.088583
20. Guido M, Roskams T, Pontisso P, Fassan M, Thung SN, Giacomelli L, Sergio A, Farinati F, Cillo U, Rugge M. Squamous cell carcinoma antigen in human liver carcinogenesis. J Clin Pathol. 61(4):445-7. 2008. doi: 10.1136/jcp.2007.051383
19. Hussein MM, Ibrahim AA, Abdella HM, Montasser IF, Hassan MI. Evaluation of serum squamous cell carcinoma antigen as a novel biomarker for diagnosis of hepatocellular carcinoma in Egyptian patients. Indian J Cancer. 45(4):167-72. 2008. doi: 10.4103/0019-509X.44666
18. Vidalino L, Quarta S, Baesso I, Fassina G, Gatta A, Pontisso P, Doria A. Squamous cell carcinoma antigen (SCCA) expression and CD27+ memory B lymphocytes in patients with chronic hepatitis C and systemic lupus erythematosus (SLE). Clin Exp Rheumatol. 26:S83. 2008.
17. Cavalletto L, Caberlotto C, Calabrese F, Pontisso P, Bernardinello E, Biasiolo A, Giacometti C, Gottardo A, Gatta A, Chemello L. Clinical significance of serum and liver tissue SCCA in chronic hepatitis C. Dig Liver Dis. 39(3):A18. 2007. doi: 10.1016/j.dld.2006.12.067
16. Fassan M, Pennelli G, Pelizzo MR, Rugge M. Primary squamous cell carcinoma of the thyroid: immunohistochemical profile and literature review. Tumori. 93(5):518-21. 2007.
15. Giannelli G, Fransvea E, Trerotoli P, Beaugrand M, Marinosci F, Lupo L, Nkontchou G, Dentico P, Antonaci S. Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients. Clin Chim Acta. 383(1-2):147-52. 2007. doi: 10.1016/j.cca.2007.05.014
14. Parenti A, Porzionato A, Pizzi S, Guzzardo V, Fassina G, Macchi V, Ninfo V, De Caro R. Expression pattern of squamous cell carcinoma antigen in oesophageal dysplasia and squamous cell carcinoma. Histol Histopathol. 22(9):989-95. 2007. doi: 10.14670/HH-22.989
13. Vidalino L, Quarta S, Baesso I, Bernardinello E, Ruvoletto M, Frezzato F, Trentin L, Fassina G, Cavalletto L, Chemello L, Gatta A, Pontisso P. Squamosus cell carcinoma antigen (SCCA) expression and CD27+ memory B lymphocytes in patients with chronic hepatitis C. J Hepatol. 46:S179. 2007. doi: 10.1016/S0168-8278(07)62069-8
12. Giacometti C, Lunardi F, Marulli G, Loy M, Rea F, Agostini M, Saetta M, Valente M, Calabrese F. Idiopathic pulmonary fibrosis: molecular and proteic detection of SCCA and TGF-beta1. Mod Pathol. 19(S3):166. 2006. doi: 10.1038/sj.modpathol.3800894
11. Quarta S, Vidalino L, Ruvoletto M, Barbera MD, Calabrese F, Valente M, Beneduce L, Gatta A, Fassina G, Pontisso P. SCCA over-expression induces cell proliferation and down-regulation of the adhesion system. J Clin Virol. 36:S193. 2006.
10. Vidalino L, Quarta S, Baesso I, Cavasin L, Bernardinello E, Ruvoletto M, Frezzato F, Trentin L, Fassina G, Cavalletto L, Chemello L, Gatta A, Pontisso P. Deregulation of squamous cell carcinoma antigen (SCCA) expression in B lymphocytes in patients with chronic hepatitis C. J Clin Virol. 36:S28. 2006.
9. Vidalino L, Quarta S, Baesso I, Cavasin L, Bernardinello E, Trentin L, Fassina G, Cavalletto L, Chemello L, Gatta A, Pontisso P. SCCA expression in PBMCs in patients with chronic hepatitis C. Dig Liver Dis. 38:854-9. 2006.
8. Beneduce L, Castaldi F, Marino M, Quarta S, Ruvoletto M, Benvegnù L, Calabrese F, Gatta A, Pontisso P, Fassina G. Squamous cell carcinoma antigen-immunoglobulin M complexes as novel biomarkers for hepatocellular carcinoma. Cancer. 103(12):2558-65. 2005. doi: 10.1002/cncr.21106
7. Giannelli G, Marinosci F, Sgarra C, Lupo L, Dentico P, Antonaci S. Clinical role of tissue and serum levels of SCCA antigen in hepatocellular carcinoma. Int J Cancer. 116(4):579-83. 2005. doi: 10.1002/ijc.20847
6. Giannelli G, Marinosci F, Trerotoli P, Volpe A, Quaranta M, Dentico P, Antonaci S. SCCA antigen combined with alpha-fetoprotein as serologic markers of HCC. Int J Cancer. 117(3):506-9. 2005. doi: 10.1002/ijc.21189
5. Pontisso P, Calabrese F, Benvegnù L, Belluco C, Ruvoletto M, Marino M, Beneduce L, Valente M, Nitti D, Alberti A, Gatta A, Fassina G. Squamous cell carcinoma antigen variants overexpression in hepatocellular carcinoma. Proceedings 11th International Symposium on Viral Hepatitis & Liver Disease. 445-6. 2004.
4. Pontisso P, Calabrese F, Benvegnù L, Lise M, Belluco C, Ruvoletto MG, Marino M, Valente M, Nitti D, Gatta A, Fassina G. Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma. Br J Cancer. 90:833-7. 2004. doi: 10.1038/sj.bjc.6601543
3. Ruvoletto MG, Tono N, Carollo D, Vilei T, Trentin L, Muraca M, Marino M, Gatta A, Fassina G, Pontisso P. Surface expression of squamous cell carcinoma antigen (SCCA) can be increased by the preS1 (21-47) sequence of hepatitis B virus. J Gen Virol. 85:621-4. 2004. doi: 10.1099/vir.0.19130-0
2. Calabrese F, Belluco C, Benvegnù L, Ruvoletto M, Valente M, Marino M, Nitti D, Alberti A, Gatta A, Fassina G, Pontisso P. High expression of serine protease inhibitor (SCCA) variants in hepatocarcinoma. Dig Liver Dis. 34(2):155. 2002. doi: 10.1016/S1590-8658(02)80250-X
1. Ruvoletto M, Marino M, Tono N, Gatta A, Fassina G, Pontisso P. Surface expression of squamous cell carcinoma antigen (SCCA) variants can be upregulated by the pre s1 (21-47) sequence of HBV. J Hepatol. 36(S1):83. 2002. doi: 10.1016/S0168-8278(02)80285-9